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Projects
Active
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Artificial Intelligence to Understand and Predict Chronic Subdural Haematoma Evolution.
Amukotuwa, S. (Primary Chief Investigator (PCI)), Lai, L. (Chief Investigator (CI)), Chandra, R. (Chief Investigator (CI)), Maier, A. (Chief Investigator (CI)), Bammer, R. (Associate Investigator (AI)), Drummond, K. J. (Associate Investigator (AI)), Hong, W. (Associate Investigator (AI)) & Straka, M. (Associate Investigator (AI))
NHMRC - National Health and Medical Research Council (Australia)
1/06/22 → 30/06/27
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Bammer, R. (Primary Chief Investigator (PCI)), Amukotuwa, S. (Chief Investigator (CI)), Chandra, R. (Chief Investigator (CI)), Drummond, K. J. (Chief Investigator (CI)), Goldschlager, T. (Chief Investigator (CI)), Thijs, V. (Chief Investigator (CI)) & Lim, K. (Chief Investigator (CI))
1/06/22 → 31/12/26
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Chandra, R. (Primary Chief Investigator (PCI))
6/04/21 → 5/04/26
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Millipede Safety and Feasibility Study.
Chandra, R. (Primary Chief Investigator (PCI))
4/03/21 → 3/03/26
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Completed
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Chandra, R. (Primary Chief Investigator (PCI))
11/03/20 → 10/03/25
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REDucing Delays In aneurysmal Subarachnoid Haemorrhage: the REDDISH study.
Gall, S. (Primary Chief Investigator (PCI)), Thrift, A. (Chief Investigator (CI)), Chandra, R. (Chief Investigator (CI)), Stirling, C. (Chief Investigator (CI)), Kinsman, L. D. (Chief Investigator (CI)), Smith, K. (Chief Investigator (CI)) & Blizzard, L. C. (Chief Investigator (CI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/18 → 31/12/21​
Research Output
2024
Clinical management of contrast-induced neurotoxicity: a systematic review.
Mariajoseph, F. P., Chung, J. X., Lai, L. T., Moore, J., Goldschlager, T., Chandra, R. V., Praeger, A. & Slater, L. A., Aug 2024, In: Acta Neurologica Belgica. 124, 4, p. 1141-1149 9 p.
Neuroradiological features of contrast-induced neurotoxicity: A systematic review and pooled analysis.
Mariajoseph, F. P., Yu, D., Lai, L. T., Moore, J., Goldschlager, T., Chandra, R. V., Praeger, A. & Slater, L. A., Aug 2024, In: Journal of Clinical Neuroscience. 126, p. 108-116 9 p.
Pathophysiology of Contrast-Induced Neurotoxicity: A Narrative Review of Possible Mechanisms.
Mariajoseph, F. P., Lai, L., Moore, J., Chandra, R., Goldschlager, T., Praeger, A. J. & Slater, L. A., Mar 2024, In: European Neurology. 87, 1, p. 26-35 10 p.
Preoperative coil localization for spinal surgery is accurate, safe and effective: a single-centre initial experience.
Kam, J. K. T., Castle-Kirszbaum, M., Dhaliwal, T., Maingard, J., Chandra, R., Quan, G., Gonzalvo, C. A. & Goldschlager, T., May 2024, In: ANZ Journal of Surgery. 94, 5, p. 840-845 6 p.
2023
Current knowledge and perspectives of contrast-induced neurotoxicity: A survey of Australian clinicians.
Mariajoseph, F. P., Lai, L. T., Moore, J., Chandra, R. V., Goldschlager, T., Praeger, A. & Slater, L. A., Oct 2023, In: Journal of Clinical Neuroscience. 116, p. 8-12 5 p.
Door-in-door-out times for patients with large vessel occlusion ischaemic stroke being transferred for endovascular thrombectomy: A Victorian state-wide study.
Wong, J. Z. W., Dewey, H. M., Campbell, B. C. V., Mitchell, P. J., Parsons, M., Phan, T., Chandra, R. V., Ma, H., Warwick, A., Brooks, M., Thijs, V., Low, E., Wijeratne, T., Jones, S., Clissold, B., Ngun, M. Y., Crompton, D., Sriamareswaran, R. K., Rupasinghe, J. & Smith, K. & 2 others, , 17 Jan 2023, In: BMJ Neurology Open. 5, 1, 8 p., 000376.
Safety and effectiveness of spinal dural defect repair in the management of superficial siderosis: A systematic review and patient-level analysis.
Mariajoseph, F. P., Castle-Kirszbaum, M., Chandra, R. V., Lai, L. T., Gonzalvo, A., Williamson, T. & Kam, J., Mar 2023, In: Journal of Clinical Neuroscience. 109, p. 44-49 6 p.
Safety and Efficacy of Tenecteplase and Alteplase in Patients With Tandem Lesion Stroke: A Post Hoc Analysis of the EXTEND-IA TNK Trials.
Yogendrakumar, V., Churilov, L., Mitchell, P. J., Kleinig, T. J., Yassi, N., Thijs, V., Wu, T., Shah, D., Bailey, P., Dewey, H. M., Choi, P. M. C., Ma, A., Wijeratne, T., Garcia-Esperon, C., Cloud, G., Chandra, R. V., Cordato, D. J., Yan, B., Sharma, G. & Desmond, P. M. & 5 others, , 2 May 2023, In: Neurology. 100, 18, p. e1900-e1911 12 p.
2022
A Meta-Analysis of Rupture Risk for Intracranial Aneurysms 10 mm or Less in Size Selected for Conservative Management Without Repair.
Chandra, R. V., Maingard, J., Slater, L. A., Cheung, N. K., Lai, L. T., Gall, S. L., Thrift, A. G. & Phan, T. G., 17 Feb 2022, In: Frontiers in Neurology. 12, 13 p., 743023.
Association of Onset-to-Treatment Time With Discharge Destination, Mortality, and Complications Among Patients With Aneurysmal Subarachnoid Hemorrhage.
Buscot, M. J., Chandra, R. V., Mainguard, J., Nichols, L., Blizzard, C. L., Stirling, C., Smith, K., Lai, L., Asadi, H., Froelich, J., Reeves, M. J., Thani, N., Thrift, A. & Gall, S., 21 Jan 2022, In: JAMA Network Open. 5, 1, p. e2144039 12 p.
Barriers and facilitators to more timely treatment of aneurysmal subarachnoid haemorrhage across two tertiary referral centres in Australia: A thematic analysis.
Nguyen, T. P., Stirling, C., Kitsos, G., Nichols, L., Chandra, R. V., Rehman, S., Smith, K., Mosley, I., Lai, L., Asadi, H., Dubey, A., Froelich, J., Thrift, A. G. & Gall, S., Sept 2022, In: Australasian Emergency Care. 25, 3, p. 267-272 6 p.
Predictors of optimal treatment time following aneurysmal subarachnoid hemorrhage across two tertiary referral centers in Australia.
Nguyen, T., Stirling, C., Nichols, L., Chandra, R., Rehman, S., Buscot, M.-J., Smith, K., Blizzard, L., Lai, L. T., Asadi, H., Dubey, A., Froelich, J., Thani, N., Reeves, M., Thrift, A. G. & Gall, S. L., 2022, In: European Stroke Journal. 7, 1S, p. 391 1 p., P0661/166.
2021
Adherence to evidence-based processes of care reduces one-year mortality after aneurysmal subarachnoid hemorrhage (aSAH).
Rehman, S., Chandra, R. V., Lai, L. T., Asadi, H., Dubey, A., Froelich, J., Thani, N., Nichols, L., Blizzard, L., Smith, K., Thrift, A. G., Stirling, C., Callisaya, M., Breslin, M., Reeves, M. J. & Gall, S., 15 Sept 2021, In: Journal of the Neurological Sciences.428, 5 p., 117613.
Advancing convergent mixed methods design using the Diamond Approach for clinical multiple case studies: an example using data on time to treatment in aneurysmal subarachnoid haemorrhage.
Nguyen, T. P., Stirling, C., Kitsos, G., Jose, K., Nichols, L., Chandra, R. V., Rehman, S., Smith, K. L., Mosley, I., Lai, L. T., Asadi, H., Dubey, A., Froelich, J., Thrift, A. G. & Gall, S., 12 Sept 2021, medRxiv preprints, 2021 30 p.
How common are seizures in the heidenhain variant of creutzfeldt-jakob disease? A case report and systematic review.
Muthusamy, S., Garg, P., Chandra, R. V. & Seneviratne, U., Apr 2021, In: Journal of Clinical Neuroscience. 86, p. 301-309 9 p.
Impact of Onset-To-Treatment Time on Hospital Discharge Destination After Aneurysmal Subarachnoid Haemorrhage-The REDDISH Study.
Buscot, M. J., Chandra, R. V., Nichols, L., Blizzard, L., Stirling, C., Smith, K. L., Lai, L. T., Asadi, H., Reeves, M. J., Froelich, J., Thani, N., Thrift, A. G. & Gall, S. L., Mar 2021, In: Stroke. 52, s1, 1 p., P37.
Intravenous milrinone for treatment of delayed cerebral ischaemia following subarachnoid haemorrhage: a pooled systematic review.
Castle-Kirszbaum, M., Lai, L., Maingard, J., Asadi, H., Danks, R. A., Goldschlager, T. & Chandra, R. V., Dec 2021, In: Neurosurgical Review. 44, 6, p. 3107-3124 18 p.
Predictive Relevance of Early Temperature Elevation on the Risk of Delayed Cerebral Ischemia Development Following Aneurysmal Subarachnoid Hemorrhage.
Saripalli, M., Tan, D., Chandra, R. V. & Lai, L. T., Jun 2021, In: World Neurosurgery. 150, p. e474-e481 8 p.
Role of vertebroplasty and balloon kyphoplasty in pathological fracture in myeloma: a narrative review.
Onggo, J. R., Maingard, J. T., Nambiar, M., Buckland, A., Chandra, R. V. & Hirsch, J. A., Oct 2021, In: European Spine Journal. 30, 10, p. 2825-2838 14 p.
The use of minimally invasive interspinous process devices for the treatment of lumbar canal stenosis: A narrative literature review.
Onggo, J. R., Nambiar, M., Maingard, J. T., Phan, K., Marcia, S., Manfrè, L., Hirsch, J. A., Chandra, R. V. & Buckland, A. J., Sept 2021, In: Journal of Spine Surgery. 7, 3, p. 394-412 19 p.
Utility of Severity-Based Prehospital Triage for Endovascular Thrombectomy: ACT-FAST Validation Study.
Zhao, H., Smith, K., Bernard, S., Stephenson, M., Ma, H., Chandra, R. V., Phan, T., Bladin, C. F., Churilov, L., Crompton, D., Dewey, H. M., Wijeratne, T., Cloud, G., Thijs, V., Kleinig, T. J., Ng, J. L., Williams, C., Alemseged, F., Ng, F. & Mitchell, P. J. & 4 others, , Jan 2021, In: Stroke. 52, 1, p. 70-79 10 p.
2020
A pituitary metastasis, an adenoma and potential hypophysitis: A case report of tumour to tumour metastasis in the pituitary.
Castle-Kirszbaum, M., Beng Phung, T., Luen, S. J., Rimmer, J., Chandra, R. V. & Goldschlager, T., Nov 2020, In: Journal of Clinical Neuroscience. 81, p. 161-166 6 p.
Asymptomatic Intracranial Aneurysms in the Elderly: Long-Term Clinical and Radiologic Follow-Up of 193 Consecutive Patients.
Huang, H., O'Neill, A. H., Chandra, R. V. & Lai, L. T., Jan 2020, In: World Neurosurgery. 133, p. e600-e608 9 p.
COILUMICA: coil embolization of a coronary artery to pulmonary artery fistula via novel dual lumen micro catheter technique.
Nambiar, M., Maingard, J., Li, K., Slater, L.-A., Chandra, R. V., Chong, W., Brooks, D. M., McGaw, D. & Asadi, H., Dec 2020, In: CVIR Endovascular. 3, 1, 5 p., 83.
Environmental sustainability in neurointerventional procedures: A waste audit.
Shum, P. L., Kok, H. K., Maingard, J., Schembri, M., Bañez, R. M. F., Van Damme, V., Barras, C., Slater, L.-A., Chong, W., Chandra, R. V., Jhamb, A., Brooks, M. & Asadi, H., Nov 2020, In: Journal of NeuroInterventional Surgery. 12, 11, p. 1053-1057 5 p.
Four-Dimensional Magnetic Resonance Imaging Assessment of Intracranial Aneurysms: A State-of-the-Art Review.
Castle-Kirszbaum, M., Maingard, J., Lim, R. P., Barras, C. D., Kok, H. K., Chandra, R. V., Chong, W. & Asadi, H., Sept 2020, In: Neurosurgery. 87, 3, p. 453-465 13 p.
Melbourne Mobile Stroke Unit and Reperfusion Therapy: Greater Clinical Impact of Thrombectomy Than Thrombolysis.
Zhao, H., Coote, S., Easton, D., Langenberg, F., Stephenson, M., Smith, K., Bernard, S., Cadilhac, D. A., Kim, J., Bladin, C. F., Churilov, L., Crompton, D. E., Dewey, H. M., Sanders, L. M., Wijeratne, T., Cloud, G., Brooks, D. M., Asadi, H., Thijs, V. & Chandra, R. V. & 10 others, , Mar 2020, In: Stroke. 51, 3, p. 922-930 9 p.
Preoperative coil localization for spinal surgery: Technical note.
Castle-Kirszbaum, M., Maingard, J., Goldschlager, T. & Chandra, R. V., Mar 2020, In: Journal of Neurosurgery: Spine. 32, 3, p. 483-487 5 p.
Response.
Castle-Kirszbaum, M., Maingard, J., Goldschlager, T. & Chandra, R. V., Jul 2020, In: Journal of Neurosurgery: Spine. 33, 1, p. 125-126 2 p.
Sex differences in aneurysmal subarachnoid haemorrhage (aSAH): aneurysm characteristics, neurological complications, and outcome.
Rehman, S., Chandra, R. V., Zhou, K., Tan, D., Lai, L., Asadi, H., Froelich, J., Thani, N., Nichols, L., Blizzard, L., Smith, K., Thrift, A. G., Stirling, C., Callisaya, M. L., Breslin, M., Reeves, M. J. & Gall, S., Sept 2020, In: Acta Neurochirurgica. 162, 9, p. 2271–2282 12 p.
Single level percutaneous vertebroplasty for vertebral hemangiomata — a review of outcomes.
Nambiar, M., Maingard, J. T., Onggo, J. R., Phan, K., Asadi, H., Brooks, D. M., Hirsch, J. A., Chandra, R. V. & Anselmetti, G., 2020, In: Pain Physician. 23, 6, p. E637-E642 6 p.
Women in interventional radiology: insights into Australia's gender gap.
Foo, M., Maingard, J., Wang, M., Kok, H. K., Chandra, R. V., Jhamb, A., Chong, W., Lee, M. J., Brooks, M. & Asadi, H., Jul 2020, In: Clinical Radiology. 75, 7, p. 560.e1-560.e7
2019
A Review of the Management of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage.
Li, K., Barras, C. D., Chandra, R. V., Kok, H. K., Maingard, J. T., Carter, N. S., Russell, J. H., Lai, L., Brooks, M. & Asadi, H., Jun 2019, In: World Neurosurgery. 126, p. 513-527 15 p.
Automated detection of intracranial large vessel occlusions on computed tomography angiography a single center experience.
Amukotuwa, S. A., Straka, M., Smith, H., Chandra, R. V., Dehkharghani, S., Fischbein, N. J. & Bammer, R., Oct 2019, In: Stroke. 50, 10, p. 2790-2798 9 p.
Carotid artery stenting: Current state of evidence and future directions.
Lamanna A, Maingard J, Barras CD, Kok HK, Handelman G, Chandra RV, Thijs V, Brooks DM, Asadi H.
Acta Neurol Scand. 2019 Apr;139(4):318-333. doi: 10.1111/ane.13062. Epub 2019 Feb 6. Review.
Direct endovascular thrombectomy and bridging strategies for acute ischemic stroke: A network meta-analysis.
Phan, K., Dmytriw, A. A., Lloyd, D., Maingard, J. M., Kok, H. K., Chandra, R. V., Brooks, M., Thijs, V., Moore, J. M., Chiu, A. H. Y., Selim, M., Goyal, M., Pereira, V. M., Thomas, A. J., Hirsch, J. A., Asadi, H. & Wang, N., May 2019, In: Journal of NeuroInterventional Surgery. 11, 5, p. 443-449 7 p.
Door-in-Door-Out Time of 60 Minutes for Stroke With Emergent Large Vessel Occlusion at a Primary Stroke Center.
Choi, P. M. C., Tsoi, A. H., Pope, A. L., Leung, S., Frost, T., Loh, P. S., Chandra, R. V., Ma, H., Parsons, M., Mitchell, P. & Dewey, H. M., Oct 2019, In: Stroke. 50, 10, p. 2829-2834 6 p.
Endovascular Retrieval of Dislodged Neurovascular Devices with a Stentriever: Case Series and Technical Review.
Zhou, K. Z., Maingard, J., Kok, H. K., Wang, J., Barras, C. D., O'hare, A., Looby, S., Brennan, P., Thornton, J., Chandra, R. V., Brooks, D. M. & Asadi, H., 1 Mar 2019, In: World Neurosurgery. 123, p. e661-e669 9 p.
Endovascular Treatment of Intracranial Aneurysms: What Does Bibliographic Analysis Tell Us About Treatment Paradigms and Predictions for the Future?
Maingard, J., Lamanna, A., Kok, H. K., Thijs, V., Hirsch, J. A., Lee, M. J., Chandra, R. V., Brooks, M. & Asadi, H., 1 Jan 2019, In: World Neurosurgery. 121, p. 259-260 2 p.
Glioblastoma Presenting as Spontaneous Subarachnoid Hemorrhage: Technical Case Note of Combined Endovascular and Microsurgical Vision-Sparing Treatment.
Tan, D., Daly, C., Xenos, C., Lai, L. T. & Chandra, R. V., Aug 2019, In: World Neurosurgery. 128, p. 426-430 5 p.
Influence of ASPECTS and endovascular thrombectomy in acute ischemic stroke: A meta-analysis.
Phan, K., Saleh, S., Dmytriw, A. A., Maingard, J., Barras, C., Hirsch, J. A., Kok, H. K., Brooks, M., Chandra, R. V. & Asadi, H., Sept 2019, In: Journal of NeuroInterventional Surgery. 11, 7, p. 664-669 6 p.
Influence of comorbidities on treatment of unruptured intracranial aneurysms in the elderly.
O'Neill AH, Chandra RV, Slater LA, Chong W, Xenos C, Danks AR, Lai LT.
J Clin Neurosci. 2019 Apr;62:38-45. doi: 10.1016/j.jocn.2019.01.013. Epub 2019 Jan 14.
Meta-Analysis of Accuracy of the Spot Sign for Predicting Hematoma Growth and Clinical Outcomes.
Phan, T. G., Krishnadas, N., Lai, V. W. Y., Batt, M., Slater, L. A., Chandra, R. V., Srikanth, V. & Ma, H., 1 Aug 2019, In: Stroke.50, 8, p. 2030-2036 7 p.
Novel Application of the Pfirrmann Disc Degeneration Grading System to 9.4T MRI: Higher Reliability Compared to 3T MRI.
Sher, I., Daly, C., Oehme, D., Chandra, R. V., Sher, M., Ghosh, P., Smith, J. & Goldschlager, T., 1 Jul 2019, In: Spine. 44, 13, p. E766-E773 8 p.
Sex differences in risk factors for aneurysmal subarachnoid haemorrhage: Systematic review and meta-analysis.
Rehman, S., Sahle, B. W., Chandra, R. V., Dwyer, M., Thrift, A. G., Callisaya, M., Breslin, M., Phan, H. T., Otahal, P. & Gall, S., 15 Nov 2019, In: Journal of the Neurological Sciences. 406, 9 p., 116446.
Surgical considerations in a paediatric case of a large skull-base epithelioid haemangioendothelioma.
Ooi, S., Gutman, M., Xenos, C., Chandra, R. & McLean, C., 4 Mar 2019, In: Child's Nervous System. 35, 3, p. 559-563 5 p.
Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual patient-level data.
Campbell BCV, Majoie CBLM, Albers GW, Menon BK, Yassi N, Sharma G, van Zwam WH, van Oostenbrugge RJ, Demchuk AM, Guillemin F, White P, Dávalos A, van der Lugt A, Butcher KS, Cherifi A, Marquering HA, Cloud G, Macho Fernández JM, Madigan J, Oppenheim C, Donnan GA, Roos YBWEM, Shankar J, Lingsma H, Bonafé A, Raoult H, Hernández-Pérez M, Bharatha A, Jahan R, Jansen O, Richard S, Levy EI, Berkhemer OA, Soudant M, Aja L, Davis SM, Krings T, Tisserand M, San Román L, Tomasello A, Beumer D, Brown S, Liebeskind DS, Bracard S, Muir KW, Dippel DWJ, Goyal M, Saver JL, Jovin TG, Hill MD, Mitchell PJ; HERMES collaborators.
Lancet Neurol. 2019 Jan;18(1):46-55. doi: 10.1016/S1474-4422(18)30314-4. Epub 2018 Nov 6. Erratum in: Lancet Neurol. 2019 Mar;18(3):e2.
Outcomes of endovascular thrombectomy with and without bridging thrombolysis for acute large vessel occlusion ischaemic stroke.
Maingard J, Shvarts Y, Motyer R, Thijs V, Brennan P, O'Hare A, Looby S, Thornton J, Hirsch JA, Barras CD, Chandra RV, Brooks M, Asadi H, Kok HK.
Intern Med J. 2019 Mar;49(3):345-351. doi: 10.1111/imj.14069
The 100 most cited articles in the endovascular management of acute ischemic stroke.
Ravindran K, Kurda D, Maingard J, Phan K, Kok HK, Thijs V, Hirsch JA, Lee MJ, Chandra RV, Brooks DM, Asadi H.
J Neurointerv Surg. 2019 Jan 17. pii: neurintsurg-2018-014600. doi: 10.1136/neurintsurg-2018-014600. [Epub ahead of print]
Endovascular Treatment of Intracranial Aneurysms: What Does Bibliographic Analysis Tell Us About Treatment Paradigms and Predictions for the Future?
Maingard J, Lamanna A, Kok HK, Thijs V, Hirsch JA, Lee MJ, Chandra RV, Brooks M, Asadi H.
World Neurosurg. 2019 Jan;121:259-260. doi: 10.1016/j.wneu.2018.10.080. Epub 2018 Oct 19. No abstract available.
Peering Into the Black Box of Artificial Intelligence: Evaluation Metrics of Machine Learning Methods.
Handelman GS, Kok HK, Chandra RV, Razavi AH, Huang S, Brooks M, Lee MJ, Asadi H.
AJR Am J Roentgenol. 2019 Jan;212(1):38-43. doi: 10.2214/AJR.18.20224. Epub 2018 Oct 17. Erratum in: AJR Am J Roentgenol. 2019 Feb;212(2):479.
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Associate Professor Ronil Chandra has authored over 150 publications and book chapters, and has lectured at more than 100 academic national and international teaching and research forums.
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